Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 12/20 | 0.41 |
| ▸ | CTPS2 | Q9NRF8 | 4/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077170 | 0.85 | CTPS1 (0.45) | CTPS1CTPS2ABL1 | |
| SCHEMBL21044163 | 0.84 | CTPS1 (0.58) | CTPS1CTPS2 | |
| SCHEMBL21076850 | 0.82 | LCK (0.39) | CTPS1CTPS2ATAD2ALDH1A1HPGD | |
| SCHEMBL21077073 | 0.77 | CTPS1 (0.48) | CTPS1CTPS2KDM4E | |
| SCHEMBL21077194 | 0.76 | CTPS1 (0.45) | CTPS1CTPS2ATAD2ABL1 | |
| SCHEMBL21077121 | 0.75 | CTPS1 (0.53) | CTPS1CTPS2 | |
| SCHEMBL22491677 | 0.75 | CTPS1 (0.65) | CTPS1CTPS2 | |
| SCHEMBL22762521 | 0.75 | CTPS1 (0.55) | CTPS1CTPS2 | |
| SCHEMBL21077116 | 0.75 | CTPS1 (0.58) | CTPS1CTPS2 | |
| SCHEMBL22491685 | 0.75 | CTPS1 (0.56) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |