Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 14/20 | 0.45 |
| ▸ | CTPS2 | Q9NRF8 | 4/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044468 | 0.84 | CTPS1 (0.63) | CTPS1CTPS2 | |
| SCHEMBL21077116 | 0.77 | CTPS1 (0.58) | CTPS1CTPS2 | |
| SCHEMBL21077029 | 0.76 | CTPS1 (0.41) | CTPS1CTPS2ABL1ATAD2 | |
| SCHEMBL21077121 | 0.76 | CTPS1 (0.53) | CTPS1CTPS2 | |
| SCHEMBL22762521 | 0.76 | CTPS1 (0.55) | CTPS1CTPS2GSK3BDYRK1APIK3CG | |
| SCHEMBL21077197 | 0.75 | CTPS1 (0.58) | CTPS1CTPS2PIK3CG | |
| SCHEMBL21077103 | 0.75 | CTPS1 (0.40) | CTPS1CTPS2ATAD2 | |
| SCHEMBL30528868 | 0.74 | CTPS1 (0.65) | CTPS1CTPS2 | |
| SCHEMBL21077031 | 0.74 | CTPS1 (0.49) | CTPS1CTPS2GSK3BDYRK1APIK3CG | |
| SCHEMBL30528729 | 0.74 | CTPS1 (0.74) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |