Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 12/20 | 0.43 |
| ▸ | CTPS2 | Q9NRF8 | 4/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076901 | 0.89 | CTPS1 (0.45) | CTPS1CTPS2PIK3CAGSK3BDYRK1A | |
| SCHEMBL21076967 | 0.89 | CTPS1 (0.56) | CTPS1CTPS2GSK3BDYRK1ACYP11B2 | |
| SCHEMBL21077070 | 0.88 | CTPS1 (0.44) | CTPS1CTPS2 | |
| SCHEMBL21077155 | 0.88 | CTPS1 (0.43) | CTPS1CTPS2CYP11B2CYP11B1 | |
| SCHEMBL21077151 | 0.87 | CTPS1 (0.48) | CTPS1CTPS2GSK3BDYRK1APIK3CG | |
| SCHEMBL21077003 | 0.86 | CTPS1 (0.56) | CTPS1CTPS2 | |
| SCHEMBL21077179 | 0.85 | CTPS1 (0.41) | CTPS1CTPS2PIK3CAGSK3BDYRK1A | |
| SCHEMBL21076892 | 0.84 | CTPS1 (0.55) | CTPS1CTPS2 | |
| SCHEMBL21044384 | 0.84 | CTPS1 (0.61) | CTPS1CTPS2 | |
| SCHEMBL21077212 | 0.82 | CTPS1 (0.44) | CTPS1CTPS2PIK3CGABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |