Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 13/20 | 0.45 |
| ▸ | CTPS2 | Q9NRF8 | 4/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077151 | 0.90 | CTPS1 (0.48) | CTPS1CTPS2GSK3BDYRK1APIK3CG | |
| SCHEMBL21077061 | 0.89 | CTPS1 (0.43) | CTPS1CTPS2GSK3BDYRK1APIK3CG | |
| SCHEMBL21077179 | 0.88 | CTPS1 (0.41) | CTPS1CTPS2GSK3BDYRK1APIK3CG | |
| SCHEMBL21076973 | 0.86 | CTPS1 (0.52) | CTPS1CTPS2 | |
| SCHEMBL21077174 | 0.86 | CTPS1 (0.44) | CTPS1CTPS2GSK3BDYRK1APIK3CG | |
| SCHEMBL21076967 | 0.85 | CTPS1 (0.56) | CTPS1CTPS2GSK3BDYRK1APIK3CG | |
| SCHEMBL21077212 | 0.84 | CTPS1 (0.44) | CTPS1CTPS2PIK3CG | |
| SCHEMBL21044434 | 0.83 | CTPS1 (0.60) | CTPS1CTPS2 | |
| SCHEMBL21076975 | 0.81 | CTPS1 (0.39) | CTPS1CTPS2GSK3BDYRK1APIK3CG | |
| SCHEMBL21077203 | 0.77 | CTPS1 (0.51) | CTPS1CTPS2ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |