Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CTPS2 | Q9NRF8 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044425 | 0.85 | CTPS1 (0.56) | CTPS1CTPS2 | |
| SCHEMBL21077210 | 0.85 | CTPS1 (0.42) | CTPS1KDM4E | |
| SCHEMBL22762461 | 0.84 | CTPS1 (0.55) | CTPS1NPC1RAB9AGAAKMT2A | |
| SCHEMBL21077111 | 0.75 | CTPS1 (0.46) | CTPS1NPC1RAB9AGAAKMT2A | |
| SCHEMBL21076874 | 0.71 | CTPS1 (0.45) | CTPS1 | |
| SCHEMBL22762590 | 0.71 | CTPS1 (0.70) | CTPS1NPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL21077078 | 0.70 | SMN1; SMN2 (0.39) | GAAKMT2AMEN1TDP1SMN1; SMN2 | |
| SCHEMBL22491694 | 0.69 | CTPS1 (0.72) | CTPS1CTPS2 | |
| SCHEMBL21044404 | 0.69 | CTPS1 (0.72) | CTPS1CTPS2 | |
| SCHEMBL22491678 | 0.69 | CTPS1 (0.72) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |