Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 5/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044272 | 0.86 | CTPS1 (0.55) | CTPS1 | |
| SCHEMBL21077181 | 0.85 | CTPS1 (0.39) | CTPS1KDM4E | |
| SCHEMBL21077201 | 0.82 | CTPS1 (0.48) | CTPS1GSK3BDYRK1APIK3CG | |
| SCHEMBL21076874 | 0.73 | CTPS1 (0.45) | CTPS1GSK3BDYRK1APIK3CG | |
| SCHEMBL21044260 | 0.72 | CTPS1 (0.73) | CTPS1 | |
| SCHEMBL21077225 | 0.71 | CTPS1 (0.43) | CTPS1KDM4E | |
| SCHEMBL21077144 | 0.71 | CTPS1 (0.55) | CTPS1GSK3BDYRK1APIK3CGXDH | |
| SCHEMBL21044425 | 0.70 | CTPS1 (0.56) | CTPS1 | |
| SCHEMBL22762461 | 0.69 | CTPS1 (0.55) | CTPS1KDM4E | |
| SCHEMBL30529007 | 0.68 | CTPS1 (0.59) | CTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |