Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 6/20 | 0.55 |
| ▸ | CTPS2 | Q9NRF8 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076918 | 0.87 | CTPS1 (0.55) | CTPS1CTPS2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21077207 | 0.86 | CTPS1 (0.69) | CTPS1CTPS2 | |
| SCHEMBL21044334 | 0.81 | CTPS1 (0.81) | CTPS1CTPS2 | |
| SCHEMBL21077137 | 0.81 | CTPS1 (0.46) | CTPS1CTPS2KDRKDM4EALDH1A1 | |
| SCHEMBL21076890 | 0.81 | CTPS1 (0.57) | CTPS1CTPS2KDREGFRFGFR1 | |
| SCHEMBL21076999 | 0.80 | CTPS1 (0.68) | CTPS1CTPS2WNT3A | |
| SCHEMBL21077047 | 0.80 | CTPS1 (0.52) | CTPS1CTPS2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21077093 | 0.79 | CTPS1 (0.55) | CTPS1CTPS2WNT3AABL1 | |
| SCHEMBL21077114 | 0.79 | CTPS1 (0.55) | CTPS1CTPS2 | |
| SCHEMBL21077175 | 0.78 | CTPS1 (0.44) | CTPS1CTPS2KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |