Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 6/20 | 0.46 |
| ▸ | CTPS2 | Q9NRF8 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076999 | 0.83 | CTPS1 (0.68) | CTPS1CTPS2WNT3A | |
| SCHEMBL21077047 | 0.82 | CTPS1 (0.52) | CTPS1CTPS2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21077186 | 0.81 | CTPS1 (0.55) | CTPS1CTPS2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21044327 | 0.80 | CTPS1 (0.70) | CTPS1CTPS2 | |
| SCHEMBL21077175 | 0.80 | CTPS1 (0.44) | CTPS1CTPS2IRAK4KDM4EALDH1A1 | |
| SCHEMBL21076918 | 0.79 | CTPS1 (0.55) | CTPS1CTPS2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21077199 | 0.79 | CTPS1 (0.53) | CTPS1CTPS2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21077207 | 0.78 | CTPS1 (0.69) | CTPS1CTPS2 | |
| SCHEMBL21076877 | 0.74 | CTPS1 (0.57) | CTPS1ALDH1A1WNT3APKM | |
| SCHEMBL21077075 | 0.72 | CTPS1 (0.64) | CTPS1SMN1; SMN2MEN1KMT2AWNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |