⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2108891 | 0.78 | — | — | |
| SCHEMBL1933053 | 0.76 | — | — | |
| SCHEMBL1933055 | 0.76 | — | — | |
| SCHEMBL20145725 | 0.72 | — | — | |
| SCHEMBL29558829 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL23048486 | 0.72 | — | — | |
| SCHEMBL10745554 | 0.69 | — | — | |
| SCHEMBL10745553 | 0.69 | — | — | |
| SCHEMBL22007925 | 0.69 | — | — | |
| SCHEMBL6374261 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010534270-A | — | — | 2010-11-04 | — | — | JP | claimed |
| EP-2185603-A2 | METHODS FOR INTRODUCTING REACTIVE SECONDARY AMINES PENDANT TO POLYMER BACKBONES THAT ARE USEFUL FOR DIAZENIUMDIOLATION | Medtronic Vascular Inc. (US) | 2010-05-19 | — | — | EP | claimed |
| US-20090222088-A1 | Secondary Amine Containing Nitric Oxide Releasing Polymer Composition | MEDTRONIC VASCULAR, INC. (US) | 2009-09-03 | — | — | US | claimed |
| US-20090028966-A1 | Methods for Introducing Reactive Secondary Amines Pendant to Polymers Backbones that are Useful for Diazeniumdiolation | MEDTRONIC VASCULAR, INC. (US) | 2009-01-29 | — | — | US | claimed |
| WO-2009014829-A2 | METHODS FOR INTRODUCING REACTIVE SECONDARY AMINES PENDANT TO POLYMER BACKBONES THAT ARE USEFUL FOR DIAZENIUMDIOLATION | MEDTRONIC VASCULAR INC. (US) | 2009-01-29 | — | — | WO | claimed |
| US-8158187-B2 | Dry diazeniumdiolation methods for producing nitric oxide releasing medical devices | MEDTRONIC VASCULAR, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-20100159119-A1 | Dry Diazeniumdiolation Methods for Producing Nitric Oxide Releasing Medical Devices | MEDTRONIC VASCULAR, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| EP-2185603-A2 | METHODS FOR INTRODUCTING REACTIVE SECONDARY AMINES PENDANT TO POLYMER BACKBONES THAT ARE USEFUL FOR DIAZENIUMDIOLATION | Medtronic Vascular Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| US-20090222088-A1 | Secondary Amine Containing Nitric Oxide Releasing Polymer Composition | MEDTRONIC VASCULAR, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090028966-A1 | Methods for Introducing Reactive Secondary Amines Pendant to Polymers Backbones that are Useful for Diazeniumdiolation | MEDTRONIC VASCULAR, INC. (US) | 2009-01-29 | — | — | US | disclosed |
| WO-2009014829-A2 | METHODS FOR INTRODUCING REACTIVE SECONDARY AMINES PENDANT TO POLYMER BACKBONES THAT ARE USEFUL FOR DIAZENIUMDIOLATION | MEDTRONIC VASCULAR INC. (US) | 2009-01-29 | — | — | WO | disclosed |