Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8259210 | 1.00 | HRH3 (0.34) | HRH3L3MBTL3L3MBTL1ALDH1A1PIM1 | |
| SCHEMBL8255509 | 0.89 | MEN1 (0.35) | HRH3L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL8259610 | 0.88 | HRH3 (0.39) | HRH3L3MBTL3L3MBTL1ALDH1A1PIM1 | |
| SCHEMBL14453903 | 0.88 | HRH3 (0.37) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL26445292 | 0.88 | HRH3 (0.37) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL24848326 | 0.88 | HRH3 (0.37) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL22456338 | 0.86 | HRH3 (0.38) | HRH3L3MBTL3L3MBTL1PIM1 | |
| SCHEMBL20906889 | 0.85 | HRH3 (0.35) | HRH3ALDH1A1 | |
| SCHEMBL12030772 | 0.85 | MC4R (0.31) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL22456332 | 0.83 | L3MBTL3 (0.39) | HRH3L3MBTL3L3MBTL1ALDH1A1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492462-A1 | AMINO PYRIMIDINE COMPOUND FOR INHIBITING PROTEIN TYROSINE KINASE ACTIVITY | Shenzhen Targetrx, Inc. (CN) | 2019-06-05 | — | — | EP | disclosed |