Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26066575 | 0.94 | EGFR (0.47) | EGFRKCNH2 | |
| SCHEMBL26025350 | 0.84 | EGFR (0.73) | EGFRKCNH2 | |
| SCHEMBL30580292 | 0.80 | EGFR (0.55) | EGFRKCNH2 | |
| SCHEMBL30580258 | 0.80 | EGFR (0.71) | EGFR | |
| SCHEMBL30580255 | 0.79 | EGFR (0.52) | EGFR | |
| SCHEMBL18369604 | 0.79 | EGFR (0.63) | EGFR | |
| SCHEMBL26027015 | 0.78 | EGFR (0.71) | EGFRKCNH2 | |
| SCHEMBL18369609 | 0.78 | EGFR (0.68) | EGFR | |
| SCHEMBL19337022 | 0.78 | EGFR (0.47) | EGFRKCNH2 | |
| SCHEMBL23728980 | 0.78 | EGFR (0.48) | EGFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492462-A1 | AMINO PYRIMIDINE COMPOUND FOR INHIBITING PROTEIN TYROSINE KINASE ACTIVITY | Shenzhen Targetrx, Inc. (CN) | 2019-06-05 | — | — | EP | disclosed |