Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20987175 | 0.89 | EGFR (0.58) | EGFR | |
| SCHEMBL30580273 | 0.89 | EGFR (0.58) | EGFR | |
| SCHEMBL21016918 | 0.88 | EGFR (0.51) | EGFR | |
| SCHEMBL18369604 | 0.81 | EGFR (0.63) | EGFR | |
| SCHEMBL30580246 | 0.79 | EGFR (0.60) | EGFR | |
| SCHEMBL21077376 | 0.79 | EGFR (0.54) | EGFR | |
| SCHEMBL18369609 | 0.79 | EGFR (0.68) | EGFR | |
| SCHEMBL19336967 | 0.78 | EGFR (0.54) | EGFR | |
| SCHEMBL17059216 | 0.78 | EGFR (0.70) | EGFR | |
| SCHEMBL30580292 | 0.78 | EGFR (0.55) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492462-B1 | AMINO PYRIMIDINE COMPOUND FOR INHIBITING PROTEIN TYROSINE KINASE ACTIVITY | SHENZHEN TARGETRX INC (CN) | 2023-08-30 | — | — | EP | disclosed |