Biotin

Biotin

SCHEMBL2107780

O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21.OCCOCCOCCO

nearest known ligand 0.79

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.79
▸ PKM P14618 2/20 0.79
▸ MEN1 O00255 1/20 0.79
▸ ABL1 P00519 1/20 0.79
▸ LMNA P02545 1/20 0.79
▸ IDE P14735 1/20 0.79
▸ MAPK1 P28482 1/20 0.79
▸ KMT2A Q03164 1/20 0.79
▸ RIN1 Q13671 1/20 0.79
▸ L3MBTL1 Q9Y468 1/20 0.79
▸ HLCS P50747 6/20 0.63
▸ FOLH1 Q04609 3/20 0.55
▸ F2 P00734 1/20 0.52
▸ PRSS1 P07477 1/20 0.52
▸ PRSS2 P07478 1/20 0.52
▸ PRSS3 P35030 1/20 0.52
▸ TPSAB1 Q15661 1/20 0.52
▸ CA12 O43570 1/20 0.48
▸ CA1 P00915 1/20 0.48
▸ CA2 P00918 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL4461484 1.00 TDP1 (0.79) TDP1PKMMEN1ABL1LMNA
Biotin SCHEMBL924563 0.99 TDP1 (0.77) TDP1PKMMEN1ABL1LMNA
Biotin SCHEMBL28797762 0.99 TDP1 (0.81) TDP1PKMMEN1ABL1LMNA
Biotin SCHEMBL28430475 0.95 TDP1 (0.71) TDP1PKMMEN1ABL1LMNA
Biotin SCHEMBL504145 0.94 TDP1 (0.69) TDP1PKMMEN1ABL1LMNA
SCHEMBL903553 0.91 TDP1 (0.83) TDP1PKMMEN1ABL1LMNA
Biotin SCHEMBL15283293 0.90 TDP1 (0.97) TDP1PKMMEN1ABL1LMNA
Biotin SCHEMBL23055065 0.89 TDP1 (1.00) TDP1PKMMEN1ABL1LMNA
Biotin SCHEMBL21981206 0.89 TDP1 (1.00) TDP1PKMMEN1ABL1LMNA
Biotin SCHEMBL38817 0.89 TDP1 (1.00) TDP1PKMMEN1ABL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114544925-A Kit and method for identifying interaction between transcription factor and chromatin in plant by using CUT & Tag technology 浙江省农业科学院 2022-05-27 — — CN claimed
CN-115916219-A Bifunctional molecules and methods of use thereof 旗舰创业股份有限公司 2023-04-04 — — CN disclosed
CN-114544925-A Kit and method for identifying interaction between transcription factor and chromatin in plant by using CUT & Tag technology 浙江省农业科学院 2022-05-27 — — CN disclosed
EP-1403254-B1 Novel applications of acridinium compounds and derivatives in homogeneous assays SIEMENS HEALTHCARE DIAGNOSTICS (US) 2014-09-17 — — EP disclosed
US-8652778-B2 Use of photopolymerization for amplification and detection of a Molecular Recognition Event THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2014-02-18 — — US disclosed
US-8159676-B2 Ratiometric surface plasmon coupled emission detector UNIVERSITY OF NORTH TEXAS, HEALTH SCIENCE CENTER AT FORT WORTH (US) 2012-04-17 — — US disclosed
US-20110251092-A1 Use of Photopolymerization for Amplification and Detection of a Molecular Recognition Event THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2011-10-13 — — US disclosed
US-20090218516-A1 Ratiometric Surface Plasmon Coupled Emission Detector UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) 2009-09-03 — — US disclosed
US-20090163371-A1 Anchor-Assisted Fragment Selection and Directed Assembly ENSEMBLE THERAPEUTICS CORPORATION 2009-06-25 — — US disclosed
US-20090163375-A1 Use of Photopolymerization for Amplification and Detection of a Molecular Recognition Event THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2009-06-25 — — US disclosed
EP-1891242-A2 ANCHOR-ASSISTED FRAGMENT SELECTION AND DIRECTED ASSEMBLY Ensemble Discovery Corporation (US) 2008-02-27 — — EP disclosed
WO-2006130669-A2 ANCHOR-ASSISTED FRAGMENT SELECTION AND DIRECTED ASSEMBLY ENSEMBLE DISCOVERY CORPORATION (US) 2006-12-07 — — WO disclosed
EP-1403254-A1 Novel applications of acridinium compounds and derivatives in homogeneous assays Bayer Healthcare, LLC (US) 2004-03-31 — — EP disclosed
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