Biotin

Biotin

SCHEMBL21981206

O=C(O)CCCC[C@H]1SC[C@@H]2NC(=O)N[C@H]21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 1.00
MEN1 O00255 1/20 1.00
ABL1 P00519 1/20 1.00
LMNA P02545 1/20 1.00
PKM P14618 1/20 1.00
IDE P14735 1/20 1.00
MAPK1 P28482 1/20 1.00
KMT2A Q03164 1/20 1.00
RIN1 Q13671 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
HLCS P50747 6/20 0.69
CA12 O43570 7/20 0.56
CA1 P00915 7/20 0.56
CA2 P00918 7/20 0.56
CA9 Q16790 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL826595 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL5376391 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL36572 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL9841217 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL410686 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL59420 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL23055065 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL20547409 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL22943835 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL3384633 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117568449-A Compositions and methods for sample processing 10X基因组学有限公司 2024-02-20 CN disclosed
CN-110592182-B Compositions and methods for sample processing 10X基因组学有限公司 2023-11-28 CN disclosed
CN-117136306-A In vitro cell-based assays for predicting pharmacokinetics and brain permeability of biological agents 基因泰克公司 2023-11-28 CN disclosed
CN-112126675-B Method and system for preparing nucleic acid sequencing library and library prepared by using same 10X基因组学有限公司 2022-09-09 CN disclosed
CN-107532211-B Method for analyzing biomolecule using external biomolecule as standard substance and kit therefor 金圣千 2022-08-23 CN disclosed
US-20210401995-A1 TECHNIQUES FOR ENHANCING THE SELECTIVITY AND EFFICACY OF ANTIMICROBIAL AND ANTICANCER POLYMER AGENTS INTERNATIONAL BUSINESS MACHINES CORPORATION 2021-12-30 US disclosed
US-11167036-B2 Techniques for enhancing the selectivity and efficacy of antimicrobial and anticancer polymer agents INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-11-09 US disclosed
CN-112126675-A Method and system for preparing nucleic acid sequencing library and library prepared by using same 10X基因组学有限公司 2020-12-25 CN disclosed
CN-107427808-B Method and system for preparing nucleic acid sequencing library and library prepared by using same 10X基因组学有限公司 2020-10-23 CN disclosed
US-20200164080-A1 TECHNIQUES FOR ENHANCING THE SELECTIVITY AND EFFICACY OF ANTIMICROBIAL AND ANTICANCER POLYMER AGENTS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2020-05-28 US disclosed
CN-110592182-A Compositions and methods for sample processing 10X基因组学有限公司 2019-12-20 CN disclosed
CN-105492607-B Compositions and methods for sample processing 10X基因组学有限公司 2019-07-02 CN disclosed
CN-107427808-A Method and system for preparing nucleic acid sequencing library and library prepared by using same 10X基因组学有限公司 2017-12-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210401995-A1 TECHNIQUES FOR ENHANCING THE SELECTIVITY AND EFFICACY OF ANTIMICROBIAL AND ANTICANCER POLYMER AGENTS BTD, HLCS, CD47 TDP1 3809/4885MEN1 2632/4885ABL1 754/4885
US-20200164080-A1 TECHNIQUES FOR ENHANCING THE SELECTIVITY AND EFFICACY OF ANTIMICROBIAL AND ANTICANCER POLYMER AGENTS BTD, HLCS, CD47 TDP1 3809/4885MEN1 2632/4885ABL1 754/4885
US-11167036-B2 Techniques for enhancing the selectivity and efficacy of antimicrobial and anticancer polymer agents BTD, HLCS, CD47 TDP1 3809/4885MEN1 2632/4885ABL1 754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.