Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16808805 | 0.87 | PYCR1 (0.32) | PYCR1 | |
| SCHEMBL2282998 | 0.82 | — | — | |
| SCHEMBL21093862 | 0.81 | — | — | |
| SCHEMBL21224483 | 0.77 | HRH3 (0.41) | DRD2POLBHRH3HTR1ADRD3 | |
| SCHEMBL5358 | 0.77 | HRH3 (0.41) | DRD2POLBHRH3HTR1ADRD3 | |
| SCHEMBL2729745 | 0.77 | HRH3 (0.41) | DRD2POLBHRH3HTR1ADRD3 | |
| SCHEMBL18163221 | 0.76 | — | — | |
| Fluoride SCHEMBL64252 | 0.73 | HRH3 (0.39) | DRD2POLBHRH3HTR1ADRD3 | |
| SCHEMBL14270553 | 0.73 | HRH3 (0.39) | DRD2POLBHRH3HTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL210163 | 0.73 | HRH3 (0.39) | DRD2POLBHRH3HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |