SCHEMBL21077937

SCHEMBL21077937

CNCC1(OC=O)CCNCC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21077936 0.89
SCHEMBL4146680 0.86
SCHEMBL19015421 0.76 KDM4E (0.31) KDM4EKMT2A
SCHEMBL26248265 0.71 KDM4E (0.30) KDM4EKMT2A
SCHEMBL8802510 0.69
SCHEMBL27609527 0.67 OPRM1 (0.30)
SCHEMBL14139395 0.65 KDM4E (0.34) KDM4EKMT2A
SCHEMBL4149511 0.64 TSHR (0.37) KDM4E
SCHEMBL17780232 0.63 KDM4E (0.38) KDM4EKMT2A
SCHEMBL12205329 0.63 KDM1A (0.40) KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3041841-B1 TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF HOFFMANN LA ROCHE (CH) 2019-06-05 EP disclosed