Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721282 | 0.88 | DRD2 (0.35) | DRD2 | |
| SCHEMBL13103020 | 0.81 | DRD2 (0.40) | DRD2FFAR3POLBNPSR1 | |
| SCHEMBL7991761 | 0.79 | — | — | |
| SCHEMBL12437229 | 0.79 | EPHX2 (0.42) | DRD2 | |
| SCHEMBL14252409 | 0.79 | DRD2 (0.39) | DRD2FFAR3POLBNPSR1 | |
| SCHEMBL14421936 | 0.79 | DRD2 (0.39) | DRD2FFAR3POLBNPSR1 | |
| SCHEMBL17886632 | 0.76 | DRD2 (0.37) | DRD2 | |
| SCHEMBL16304087 | 0.76 | DRD2 (0.37) | DRD2 | |
| SCHEMBL16306650 | 0.76 | DRD2 (0.46) | DRD2POLBNPSR1 | |
| SCHEMBL1446029 | 0.75 | HTT (0.38) | DRD2FFAR3POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |