SCHEMBL21078403

SCHEMBL21078403

O=C(CP)OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
USP2 O75604 1/20 0.46
MAPT P10636 1/20 0.46
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18518602 0.83 TSHR (0.49) TSHRUSP2MAPTCYP1A2CYP2C9
SCHEMBL18927425 0.83 TSHR (0.46) TSHRUSP2MAPTCYP1A2CYP2C9
SCHEMBL24470981 0.82 THRB (0.34)
SCHEMBL13610609 0.81 TSHR (0.47) TSHRUSP2MAPTCYP1A2CYP2C9
SCHEMBL9560553 0.81 TSHR (0.44) TSHRUSP2MAPTCYP1A2CYP2C9
SCHEMBL19181772 0.81 TSHR (0.44) TSHRUSP2MAPTCYP1A2CYP2C9
SCHEMBL9560780 0.81 TSHR (0.44) TSHRUSP2MAPTCYP1A2CYP2C9
SCHEMBL9560795 0.81 TSHR (0.44) TSHRUSP2MAPTCYP1A2CYP2C9
SCHEMBL11750407 0.79 TSHR (0.48) TSHRUSP2MAPTCYP1A2CYP2C9
SCHEMBL11750251 0.79 TSHR (0.48) TSHRUSP2MAPTCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10908338-B2 Optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2021-02-02 US disclosed
US-20190170922-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2019-06-06 US disclosed