Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137567 | 0.97 | TSHR (0.36) | TSHRBBOX1ALDH1A1SLC22A1 | |
| Iodide SCHEMBL14836997 | 0.95 | TSHR (0.35) | TSHRBBOX1ALDH1A1SLC22A1 | |
| Bromide SCHEMBL10506970 | 0.95 | TSHR (0.35) | TSHRBBOX1ALDH1A1SLC22A1 | |
| Hydrochloric Acid SCHEMBL11699399 | 0.93 | TSHR (0.31) | TSHR | |
| SCHEMBL28169517 | 0.92 | TSHR (0.36) | TSHRBBOX1ALDH1A1SLC22A1 | |
| Hydrochloric Acid SCHEMBL27511966 | 0.90 | TSHR (0.32) | TSHRBBOX1 | |
| Water SCHEMBL27840701 | 0.90 | TSHR (0.35) | TSHRBBOX1ALDH1A1SLC22A1 | |
| SCHEMBL14312219 | 0.87 | TSHR (0.33) | TSHRBBOX1ALDH1A1SLC22A1 | |
| Hydrochloric Acid SCHEMBL27872561 | 0.86 | TSHR (0.37) | TSHRBBOX1ALDH1A1SLC22A1 | |
| Hydrochloric Acid SCHEMBL9282607 | 0.85 | TSHR (0.40) | TSHRBBOX1ALDH1A1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117467093-A | High-temperature-resistant filtrate reducer as well as preparation method and application thereof | 中国石油天然气集团有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-114891156-B | Series methyl alkyl substituent diallyl ammonium chloride copolymer demulsifier and preparation method thereof | 南京理工大学 | 2022-12-06 | — | — | CN | claimed |
| CN-114891156-A | Series methyl alkyl substituent diallyl ammonium chloride copolymer demulsifier and preparation method thereof | 南京理工大学 | 2022-08-12 | — | — | CN | claimed |
| US-20080076851-A1 | Hydrophilic surface modification of contact lenses | GOLDBERG EUGENE P | 2008-03-27 | — | — | US | claimed |
| CN-117467093-A | High-temperature-resistant filtrate reducer as well as preparation method and application thereof | 中国石油天然气集团有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117467093-A | High-temperature-resistant filtrate reducer as well as preparation method and application thereof | 中国石油天然气集团有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-114891156-B | Series methyl alkyl substituent diallyl ammonium chloride copolymer demulsifier and preparation method thereof | 南京理工大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-114891156-A | Series methyl alkyl substituent diallyl ammonium chloride copolymer demulsifier and preparation method thereof | 南京理工大学 | 2022-08-12 | — | — | CN | disclosed |
| EP-2578618-B1 | METHOD FOR PRODUCING COPOLYMER OF DIALLYLAMINE AND SULFUR DIOXIDE | NITTO BOSEKI CO LTD (JP) | 2019-01-30 | — | — | EP | disclosed |
| CN-104327218-B | A kind of preparation method of PAMC aqueous emulsion | 山东德仕石油工程集团股份有限公司 | 2017-03-08 | — | — | CN | disclosed |
| US-9006383-B2 | Method for producing copolymer of diallylamine and sulfur dioxide | NITTO BOSEKI CO., LTD. (JP) | 2015-04-14 | — | — | US | disclosed |
| CN-102892811-B | Method for producing copolymer of diallylamine and sulfur dioxide | NITTO BOSEKI CO LTD | 2015-04-01 | — | — | CN | disclosed |
| WO-1992013912-A1 | AGGLOMERATED POLYMER PARTICLES PRODUCED FROM FINELY DIVIDED WATER-SOLUBLE OR WATER-SWELLABLE POLYMERISATES | BASF AKTIENGESELLSCHAFT (DE) | 1992-08-20 | — | — | WO | disclosed |
| EP-0412388-A2 | Process of preparation of fine particles of polymers in powder form | BASF Aktiengesellschaft (DE) | 1991-02-13 | — | — | EP | disclosed |
| EP-0290753-B1 | PROCESS FOR PREPARING POLYMER BEADS FROM WATER-SOLUBLE ETHYLENICALLY UNSATARATED MONOMERS | BASF Aktiengesellschaft (DE) | 1990-12-19 | — | — | EP | disclosed |
| WO-1990011304-A1 | PROCESS FOR REDUCING THE RESIDUAL MONOMER CONTENT OF DIALLYL AMMONIUM SALT POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-04 | — | — | WO | disclosed |
| US-4879361-A | PAPERMAKING, FLOCCULATION, ABSORBTION | BASF AKTIENGESELLSCHAFT (DE) | 1989-11-07 | — | — | US | disclosed |
| EP-0290753-A1 | Process for preparing polymer beads from water-soluble ethylenically unsatarated monomers | BASF Aktiengesellschaft (DE) | 1988-11-17 | — | — | EP | disclosed |
| EP-0196588-A2 | Process for the preparation of copolymers of N-substituted secondary monoallylamines or salts thereof | NITTO BOSEKI CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4331447-A | ADDING AN OIL FRACTION AS A BINDER TO AN AQUEOUS SLURRY | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-25 | — | — | US | disclosed |