⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721582 | 0.88 | — | — | |
| SCHEMBL15813512 | 0.82 | — | — | |
| SCHEMBL3373630 | 0.75 | — | — | |
| SCHEMBL1751567 | 0.72 | — | — | |
| SCHEMBL19292 | 0.72 | — | — | |
| SCHEMBL13831358 | 0.72 | — | — | |
| SCHEMBL19443 | 0.72 | — | — | |
| SCHEMBL14993133 | 0.67 | — | — | |
| SCHEMBL18057016 | 0.62 | — | — | |
| SCHEMBL15179655 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228590-A1 | SIMPLIFIED RADIOSYNTHESIS OF [18F]FLUOROMETHYL BROMIDE | PIRAMAL IMAGING SA (CH) | 2014-08-14 | — | — | US | claimed |
| EP-2748134-A1 | SIMPLIFIED RADIOSYNTHESIS OF [18F]FLUOROMETHYL BROMIDE | Piramal Imaging SA (CH) | 2014-07-02 | — | — | EP | claimed |
| WO-2013026941-A1 | SIMPLIFIED RADIOSYNTHESIS OF [18F]FLUOROMETHYL BROMIDE | PIRAMAL IMAGING SA (CH) | 2013-02-28 | — | — | WO | claimed |
| US-20140296566-A1 | Simplified Radiosynthesis of O-[18F]Fluoromethyl Tyrosine Derivatives | PIRAMAL IMAGING SA (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140228590-A1 | SIMPLIFIED RADIOSYNTHESIS OF [18F]FLUOROMETHYL BROMIDE | PIRAMAL IMAGING SA (CH) | 2014-08-14 | — | — | US | disclosed |
| EP-2748134-A1 | SIMPLIFIED RADIOSYNTHESIS OF [18F]FLUOROMETHYL BROMIDE | Piramal Imaging SA (CH) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026941-A1 | SIMPLIFIED RADIOSYNTHESIS OF [18F]FLUOROMETHYL BROMIDE | PIRAMAL IMAGING SA (CH) | 2013-02-28 | — | — | WO | disclosed |
| WO-2012025464-A1 | FLUORODEUTERIOMETHYL TYROSINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-01 | — | — | WO | disclosed |