SCHEMBL2107918

SCHEMBL2107918

C=CCC1C(CC=C)N1CC=C

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16767751 0.70 CHRNB2 (0.37)
SCHEMBL2107962 0.70 PRCP (0.31)
SCHEMBL15662580 0.69 CYP3A4 (0.35) CYP3A4
SCHEMBL5135057 0.67 CYP3A4 (0.41) CYP3A4
SCHEMBL16767764 0.67 CHRNB2 (0.35)
SCHEMBL10472229 0.67 CYP3A4 (0.33) CYP3A4
SCHEMBL308887 0.67 CYP3A4 (0.33) CYP3A4
SCHEMBL2109006 0.66 MAPT (0.32)
SCHEMBL4508544 0.64 MAPT (0.31)
SCHEMBL27724451 0.64 MAPT (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9290599-B2 Functionalized polymers and tires therefrom BRIDGESTONE CORPORATION (JP) 2016-03-22 US disclosed
US-8618223-B2 Functionalized polymers and tires therefrom BRIDGESTONE CORPORATION (JP) 2013-12-31 US disclosed
US-20120180937-A1 FUNCTIONALIZED POLYMERS AND TIRES THEREFROM BRIDGESTONE CORPORATION (JP) 2012-07-19 US disclosed
US-8158725-B2 Functionalized polymers and tires therefrom BRIDGESTONE CORPORATION (JP) 2012-04-17 US disclosed
US-20070055024-A1 Functionalized polymers and tires therefrom BRIDGESTONE CORPORATION (JP) 2007-03-08 US disclosed