Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.60 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.60 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.60 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.60 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101977 | 1.00 | SSTR1 (0.60) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL3467442 | 1.00 | SSTR1 (0.60) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL19101982 | 1.00 | SSTR1 (0.60) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL15960190 | 1.00 | SSTR1 (0.60) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL13005442 | 1.00 | SSTR1 (0.60) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL18542464 | 1.00 | SSTR1 (0.60) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL1772243 | 1.00 | SSTR1 (0.60) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL13005383 | 1.00 | SSTR1 (0.60) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL21440458 | 1.00 | SSTR1 (0.60) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL38652118 | 1.00 | SSTR1 (0.60) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10765648-B2 | iNKT cell modulators and methods of using the same | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2020-09-08 | — | — | US | disclosed |
| US-10314796-B2 | iNKT cell modulators and methods of using the same | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2019-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10765648-B2 | iNKT cell modulators and methods of using the same | PBK, NFATC1, UGCG | SSTR1 2519/4885SSTR2 2747/4885SSTR4 2348/4885 |
| US-10314796-B2 | iNKT cell modulators and methods of using the same | PBK, NFATC1, UGCG | SSTR1 2519/4885SSTR2 2747/4885SSTR4 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.