SCHEMBL1772243

SCHEMBL1772243

CO[C@H]1O[C@H](CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1OCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SSTR1 P30872 1/20 0.60
SSTR2 P30874 1/20 0.60
SSTR4 P31391 1/20 0.60
SSTR3 P32745 1/20 0.60
SSTR5 P35346 1/20 0.60
BCHE P06276 1/20 0.57
LGALS8 O00214 1/20 0.50
PTPN1 P18031 5/20 0.49
PTPN2 P17706 4/20 0.49
SLC6A2 P23975 1/20 0.48
TACR2 P21452 1/20 0.46
CDC25B P30305 3/20 0.44
PDPK1 O15530 1/20 0.43
MTOR P42345 1/20 0.43
LGALS3 P17931 1/20 0.43
CDC25A P30304 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19101977 1.00 SSTR1 (0.60) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL3467442 1.00 SSTR1 (0.60) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL19101982 1.00 SSTR1 (0.60) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL15960190 1.00 SSTR1 (0.60) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL13005442 1.00 SSTR1 (0.60) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL18542464 1.00 SSTR1 (0.60) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL13005383 1.00 SSTR1 (0.60) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL21440458 1.00 SSTR1 (0.60) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL21082185 1.00 SSTR1 (0.60) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL38652118 1.00 SSTR1 (0.60) SSTR1SSTR2SSTR4SSTR3SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651903-A1 M6PR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
CN-113164501-B Use of agonist ligands for IGF-2 receptor for the treatment of An Geman syndrome and autism 纽约大学 2024-08-09 CN disclosed
WO-2024155748-A1 M6PR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed
EP-4370156-A1 M6PR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2024-05-22 EP disclosed
EP-4356964-A2 USE OF IGF-2 RECEPTOR AGONIST LIGANDS FOR TREATMENT OF ANGELMAN SYNDROME AND AUTISM New York University (US) 2024-04-24 EP disclosed
CN-117915956-A M6PR cell surface receptor binding compounds and conjugates 利西亚治疗公司 2024-04-19 CN disclosed
EP-3833358-B1 USE OF IGF-2 RECEPTOR AGONIST LIGANDS FOR TREATMENT OF ANGELMAN SYNDROME AND AUTISM UNIV NEW YORK (US) 2023-12-06 EP disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 US disclosed
WO-2023288015-A1 M6PR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2023-01-19 WO disclosed
EP-4087584-A2 CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2022-11-16 EP disclosed
CN-112912102-A Use of mannose-6-phosphate and modifications thereof to enhance memory and reduce memory impairment 纽约大学 2021-06-04 CN disclosed
US-20130164387-A9 NOVEL MANNOPYRANOSIDE DERIVATIVES WITH ANTICANCER ACTIVITY CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-06-27 US disclosed
US-20120269903-A1 NOVEL MANNOPYRANOSIDE DERIVATIVES WITH ANTICANCER ACTIVITY CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2012-10-25 US disclosed
US-20110112044-A1 NOVEL USES OF D-MANNOPYRANOSE DERIVATIVES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-05-12 US disclosed
US-7208611-B2 Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use XENOPORT, INC. (US) 2007-04-24 US disclosed
US-20060205677-A1 Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use XENOPORT, INC. 2006-09-14 US disclosed
WO-2006091790-A1 PLATINUM-CONTAINING COMPOUNDS EXHIBITING CYTOSTATIC ACTIVITY, SYNTHESIS AND METHODS OF USE XENOPORT, INC. (US) 2006-08-31 WO disclosed
EP-0545198-B1 Peptides with insulin like activity HOECHST AG (DE) 1999-09-15 EP disclosed
US-5622934-A TREATING DIABETES MELLITUS HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-22 US disclosed
EP-0545198-A2 Peptides with insulin like activity HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060205677-A1 Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use TYMP, TOP1, TOP2A SSTR1 4740/4885SSTR2 4809/4885SSTR4 4747/4885
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R SSTR1 347/4885SSTR2 704/4885SSTR4 239/4885
US-20130164387-A9 NOVEL MANNOPYRANOSIDE DERIVATIVES WITH ANTICANCER ACTIVITY MAN2A1, MANBA, MAN2B1 SSTR1 4137/4885SSTR2 3782/4885SSTR4 4057/4885
US-20110112044-A1 NOVEL USES OF D-MANNOPYRANOSE DERIVATIVES M6PR, BMP6, DCPS SSTR1 1791/4885SSTR2 2335/4885SSTR4 1290/4885
US-20120269903-A1 NOVEL MANNOPYRANOSIDE DERIVATIVES WITH ANTICANCER ACTIVITY MAN2A1, MANBA, MAN2B1 SSTR1 4137/4885SSTR2 3782/4885SSTR4 4057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.