Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24732254 | 0.81 | HPGD (0.55) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL25865367 | 0.73 | HPGD (0.59) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL11125037 | 0.73 | HPGD (0.63) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL5766105 | 0.73 | HPGD (0.63) | HPGDALDH1A1NPC1RAB9AALOX12 | |
| SCHEMBL959541 | 0.72 | NPC1 (0.77) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL13433106 | 0.70 | NPC1 (0.61) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL20035718 | 0.70 | NPC1 (0.55) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL18599981 | 0.69 | HPGD (0.53) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL15394679 | 0.68 | HPGD (0.56) | HPGDALDH1A1NPC1RAB9AALOX12 | |
| SCHEMBL22787322 | 0.67 | HPGD (0.61) | HPGDALDH1A1NPC1RAB9ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492473-A1 | HAPTENS OF OLANZIPINE | Janssen Pharmaceutica NV (BE) | 2019-06-05 | — | — | EP | disclosed |