Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EBP | Q15125 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11125037 | 0.83 | HPGD (0.63) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL24938674 | 0.82 | NPC1 (0.60) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL18599981 | 0.82 | HPGD (0.53) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL959541 | 0.82 | NPC1 (0.77) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL12139537 | 0.81 | NPC1 (0.57) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL13433106 | 0.80 | NPC1 (0.61) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL8432028 | 0.80 | RAB9A (0.62) | HPGDALDH1A1NPC1RAB9APOLB | |
| SCHEMBL14223269 | 0.76 | HPGD (0.55) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL14223256 | 0.76 | HPGD (0.55) | HPGDALDH1A1NPC1RAB9ASIGMAR1 | |
| SCHEMBL24732254 | 0.76 | HPGD (0.55) | HPGDALDH1A1NPC1RAB9ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017977-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-01-25 | — | — | WO | disclosed |
| WO-2023135582-A1 | NEW STEREORETENTIVE RUTHENIUM COMPLEXES, METHOD OF THEIR PREPARATION, INTERMEDIATES USED IN THIS METHOD AND USE OF NEW STEREORETENTIVE RUTHENIUM COMPLEXES IN OLEFIN METATHESIS REACTIONS | UNIWERSYTET WARSZAWSKI (PL) | 2023-07-20 | — | — | WO | disclosed |