Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | AHCY | P23526 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21138875 | 1.00 | YTHDC1 (0.56) | YTHDC1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL18410858 | 0.87 | YTHDC1 (0.60) | YTHDC1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL22524099 | 0.86 | YTHDC1 (0.59) | YTHDC1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2041441 | 0.86 | YTHDC1 (0.59) | YTHDC1ADORA3AHCY | |
| SCHEMBL29318369 | 0.86 | YTHDC1 (0.59) | YTHDC1ADORA3AHCY | |
| SCHEMBL23584826 | 0.83 | YTHDC1 (0.55) | YTHDC1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL22524035 | 0.79 | YTHDC1 (0.50) | YTHDC1ADORA3ADORA2AADORA2BADORA1 | |
| Phenol SCHEMBL27699602 | 0.79 | ABL1 (0.52) | YTHDC1ADORA3NR2F2 | |
| SCHEMBL20324865 | 0.79 | P2RY1 (0.59) | YTHDC1ADORA3 | |
| SCHEMBL22687460 | 0.77 | P2RY1 (0.51) | YTHDC1ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015005-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | ModernaTX, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| EP-3682905-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | ModernaTX, Inc. (US) | 2020-07-22 | — | — | EP | disclosed |
| EP-3492109-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | Moderna Therapeutics, Inc. (US) | 2019-06-05 | — | — | EP | disclosed |