Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB3 | P54753 | 1/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.51 |
| ▸ | JAK1 | P23458 | 14/20 | 0.44 |
| ▸ | JAK3 | P52333 | 14/20 | 0.44 |
| ▸ | JAK2 | O60674 | 13/20 | 0.44 |
| ▸ | TYK2 | P29597 | 13/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13139955 | 0.85 | EPHB3 (0.56) | EPHB3TGFBR1TLR8LMNAHTT | |
| SCHEMBL3073610 | 0.85 | EPHB3 (0.56) | EPHB3TGFBR1LMNAHTT | |
| SCHEMBL16795174 | 0.84 | EPHB3 (0.49) | EPHB3TGFBR1TLR8JAK1JAK3 | |
| SCHEMBL13139980 | 0.83 | EPHB3 (0.62) | EPHB3TGFBR1LMNAHTT | |
| SCHEMBL17632551 | 0.82 | TGFBR1 (0.50) | EPHB3TGFBR1TLR8JAK1JAK3 | |
| SCHEMBL19657530 | 0.81 | EPHB3 (0.63) | EPHB3TGFBR1JAK2LMNAHTT | |
| SCHEMBL17320982 | 0.81 | EPHB3 (0.56) | EPHB3TGFBR1LMNAHTT | |
| SCHEMBL17067859 | 0.81 | TGFBR1 (0.49) | EPHB3TGFBR1TLR8JAK1JAK3 | |
| SCHEMBL17067855 | 0.81 | TGFBR1 (0.49) | EPHB3TGFBR1TLR8JAK1JAK3 | |
| SCHEMBL22955512 | 0.80 | TGFBR1 (0.49) | EPHB3TGFBR1TLR8JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219453-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
| EP-3492461-A1 | NITROGENOUS HETEROCYCLIC AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF | Shanghai Yingli Pharmaceutical Co. Ltd. (CN) | 2019-06-05 | — | — | EP | disclosed |