SCHEMBL21084263

SCHEMBL21084263

CCN(CCCN1C(=O)c2ccccc2C1=O)Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 1.00
ACHE P22303 7/20 0.92
BCHE P06276 4/20 0.92

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23418082 0.91 MAOB (1.00) MAOBACHEBCHE
SCHEMBL9824940 0.91 MAOB (0.83) MAOBACHEBCHE
SCHEMBL8131752 0.91 MAOB (0.83) MAOBACHEBCHE
SCHEMBL9317694 0.87 MAOB (0.78) MAOBACHEBCHE
SCHEMBL8398570 0.87 MAOB (0.84) MAOBACHEBCHE
SCHEMBL31020795 0.84 MAOB (0.72) MAOBACHEBCHE
SCHEMBL14030727 0.82 MAOB (1.00) MAOBACHEBCHE
SCHEMBL9416046 0.82 MAOB (0.74) MAOBACHEBCHE
SCHEMBL9415916 0.82 MAOB (0.74) MAOBACHEBCHE
SCHEMBL9416026 0.82 MAOB (0.74) MAOBACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3530259-B1 DENTAL COMPOSITION DENTSPLY DETREY GMBH (DE) 2024-12-25 EP disclosed
CN-111683640-B dental composition 登士柏希罗纳有限公司 2023-10-27 CN disclosed
US-10849831-B2 Dental composition DENTSPLY SIRONA INC. (US) 2020-12-01 US disclosed
US-10849831-B2 Dental composition DENTSPLY SIRONA INC. (US) 2020-12-01 US disclosed
CN-111683640-A Dental composition 登士柏希罗纳有限公司 2020-09-18 CN disclosed
EP-3530259-A1 DENTAL COMPOSITION Dentsply DeTrey GmbH (DE) 2019-08-28 EP disclosed
EP-3530259-A1 DENTAL COMPOSITION Dentsply DeTrey GmbH (DE) 2019-08-28 EP disclosed
WO-2019136060-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2019-07-11 WO disclosed
US-20190201297-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2019-07-04 US disclosed
US-20190201297-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2019-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10849831-B2 Dental composition B2M, ITGB3, HBG1 MAOB 3590/4885ACHE 4677/4885BCHE 4212/4885
US-20190201297-A1 DENTAL COMPOSITION B2M, ITGB3, HBG1 MAOB 3590/4885ACHE 4677/4885BCHE 4212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.