Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25978589 | 0.93 | PAOX (0.52) | PAOXTSHRALDH1A1CYP2C19MEN1 | |
| SCHEMBL18681683 | 0.91 | PAOX (0.50) | PAOXTSHRALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL20960756 | 0.91 | PAOX (0.50) | PAOXTSHRALDH1A1CYP2C19CYP1A2 | |
| Hydrochloric Acid SCHEMBL22771730 | 0.83 | PAOX (0.40) | PAOXTSHRALDH1A1THRATHRB | |
| SCHEMBL8675626 | 0.83 | — | — | |
| SCHEMBL24040956 | 0.82 | ALDH1A1 (0.56) | PAOXTSHRALDH1A1S1PR1S1PR3 | |
| SCHEMBL20648073 | 0.82 | ALDH1A1 (0.56) | PAOXTSHRALDH1A1S1PR1S1PR3 | |
| SCHEMBL22735242 | 0.82 | ALDH1A1 (0.56) | PAOXTSHRALDH1A1S1PR1S1PR3 | |
| SCHEMBL29326851 | 0.81 | CA12 (0.50) | PAOXTSHRALDH1A1CYP2C19MEN1 | |
| SCHEMBL20118878 | 0.81 | TSHR (0.48) | PAOXTSHRALDH1A1CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190167407-A1 | DEVICES AND METHODS FOR LUNG VOLUME REDUCTION | SHIFAMED HOLDINGS LLC (US) | 2019-06-06 | — | — | US | disclosed |