SCHEMBL21084448

SCHEMBL21084448

CC=CC(=O)Oc1ccc(C2(c3ccc(OC(=O)C=CC)c(-c4ccccc4)c3)c3ccccc3-c3ccccc32)cc1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
PTGDR2 Q9Y5Y4 6/20 0.34
KDM4E B2RXH2 3/20 0.34
MAPT P10636 2/20 0.34
THRB P10828 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
BACE1 P56817 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 2/20 0.33
OPRK1 P41145 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
FABP3 P05413 2/20 0.32
FABP7 O15540 1/20 0.32
FABP5 Q01469 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21084452 0.89 ESR1 (0.44) MEN1KMT2APOLBESR1ESR2
SCHEMBL20752930 0.85 KMT2A (0.39) MEN1KMT2APOLBESR1ESR2
SCHEMBL2296144 0.84 KDM4E (0.40) MEN1KMT2APOLBPTGDR2KDM4E
SCHEMBL26136251 0.83 ESR1 (0.40) MEN1KMT2APOLBESR1ESR2
SCHEMBL20721760 0.81 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1
SCHEMBL21084455 0.81 MEN1 (0.39) MEN1KMT2APOLBESR1ESR2
SCHEMBL21405707 0.81 MEN1 (0.50) MEN1KMT2APOLBESR1ESR2
SCHEMBL21405705 0.81 MEN1 (0.50) MEN1KMT2APOLBESR1ESR2
SCHEMBL17148016 0.80 BACE1 (0.44) MEN1KMT2AESR1ESR2KDM4E
SCHEMBL12279930 0.79 KMT2A (0.47) MEN1KMT2APOLBESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3508924-B1 PHOTOSENSITIVE COMPOSITION FOR HOLOGRAM RECORDING, HOLOGRAM RECORDING MEDIUM, AND HOLOGRAM SONY GROUP CORP (JP) 2022-05-04 EP disclosed
EP-3508924-A1 PHOTOSENSITIVE COMPOSITION FOR HOLOGRAM RECORDING, HOLOGRAM RECORDING MEDIUM, AND HOLOGRAM Sony Corporation (JP) 2019-07-10 EP disclosed
US-20190202946-A1 PHOTOSENSITIVE COMPOSITION FOR HOLOGRAM RECORDING, HOLOGRAM RECORDING MEDIUM, AND HOLOGRAM SONY CORPORATION (JP) 2019-07-04 US disclosed