SCHEMBL21085

SCHEMBL21085

[CH2]C(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5527753 0.93
SCHEMBL28638900 0.93
SCHEMBL28766969 0.93
SCHEMBL17456394 0.83
SCHEMBL17456614 0.77
SCHEMBL394668 0.72
SCHEMBL477927 0.72
SCHEMBL18931 0.72
SCHEMBL67866 0.72
SCHEMBL20803 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 42681 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4039690-B1 A SUBSTANTIALLY DIASTEREOMERICALLY PURE PHOSPHORAMIDOCHLORIDATE, A METHOD AND A PHARMACEUTICAL COMPOSITION EISAI R&D MAN CO LTD (JP) 2024-07-17 EP claimed
CN-118344315-A Preparation and application of trifluoro thioether (sulfoxide) aromatic amine derivative 顺毅股份有限公司 2024-07-16 CN claimed
WO-2024146383-A1 CYP11A1 INHIBITOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海闻耐医药科技有限公司 2024-07-11 WO claimed
CN-118307519-A CYP11A1 inhibitor compound, preparation method and application thereof 上海闻耐医药科技有限公司 2024-07-09 CN claimed
US-20240208992-A1 MACROCYCLES AS CFTR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-27 US claimed
CN-118164894-A Synthesis method of 3-aminoindole compound 成都理工大学 2024-06-11 CN claimed
CN-118146056-A Catalytic synthesis method of nitrogen-containing aromatic heterocyclic chlorinated organic compound 河北威远生物化工有限公司 2024-06-07 CN claimed
WO-2024110477-A2 SYNTHESIS OF A CYCLIC PEPTIDE JANSSEN PHARMACEUTICA NV (BE) 2024-05-30 WO claimed
CN-118103377-A Compounds constituting C20 modified salinomycin derivatives, process for obtaining the compounds, compositions containing the compounds and uses of said compounds 菲莱克洛有限责任公司 2024-05-28 CN claimed
US-20240158417-A1 SUBSTITUTED HETEROCYCLIC FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) 2024-05-16 US claimed
US-3946005-A BACTERICIDES SMITHKLINE CORPORATION (US) 1976-03-23 US claimed
US-3944544-A BACTERICIDE E. R. SQUIBB & SONS, INC. (US) 1976-03-16 US claimed
US-3943129-A BACTERICIDE SMITHKLINE CORPORATION (US) 1976-03-09 US claimed
US-3943126-A Process for acylating a 7-aminocephalosporin ELI LILLY AND COMPANY (US) 1976-03-09 US claimed
US-3936446-A Isocyanocephalosporanates BEECHAM GROUP LIMITED (DT) 1976-02-03 US claimed
US-3936447-A 7-Acylamino-desacetoxy-cephalosporanic acid esters and their production BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed
US-3935198-A BY HEATING THE PENICILLIN SULFOXIDE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-01-27 US claimed
US-3933806-A Cephalosporin michael adducts ELI LILLY AND COMPANY (US) 1976-01-20 US claimed
US-3932393-A 3-Methylenecephalosporins and process for production thereof ELI LILLY AND COMPANY (US) 1976-01-13 US claimed
US-3932391-A Cephalosporin isocyanates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-13 US claimed