⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20803 | 0.88 | — | — | |
| SCHEMBL572196 | 0.78 | — | — | |
| SCHEMBL1527740 | 0.78 | — | — | |
| SCHEMBL1019581 | 0.78 | — | — | |
| SCHEMBL588690 | 0.78 | — | — | |
| SCHEMBL8660208 | 0.78 | — | — | |
| SCHEMBL1012277 | 0.78 | — | — | |
| SCHEMBL589093 | 0.78 | — | — | |
| SCHEMBL21268077 | 0.78 | — | — | |
| Ethylene SCHEMBL4491406 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7537 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986235-A | P53-Y220C selective small molecule reactivation agent compound, pharmaceutical composition and application thereof | 长春金赛药业有限责任公司 | 2024-05-07 | — | — | CN | claimed |
| EP-4334313-A1 | DIAZEPANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND USES THEREOF FOR THE AMELIORATION, PREVENTION AND/OR TREATMENT OF MENTAL AND NEUROLOGICAL DISEASES | 2N Pharma ApS (DK) | 2024-03-13 | — | — | EP | claimed |
| CN-117337287-A | Diazepan derivatives, process for their preparation and their use for improving, preventing and/or treating mental and neurological disorders | 2N制药公司 | 2024-01-02 | — | — | CN | claimed |
| CN-117062815-A | VMAT2 inhibitors and methods of use | 纽罗克里生物科学有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-112088160-B | 1-imidazothiadiazolo-2H-pyrrol-5-one derivatives | UCB生物制药有限责任公司 | 2023-07-04 | — | — | CN | claimed |
| EP-4168409-A1 | VMAT2 INHIBITORS AND METHODS OF USE | Neurocrine Biosciences, Inc. (US) | 2023-04-26 | — | — | EP | claimed |
| EP-3790885-B1 | 1-IMIDAZOTHIADIAZOLO-2H-PYRROL-5-ONE DERIVATIVES | UCB Biopharma SRL (BE) | 2023-04-19 | — | — | EP | claimed |
| CN-110869374-B | 2-oxo-1, 3-oxazolidinyl imidazothiadiazole derivatives | UCB生物制药有限责任公司 | 2022-08-30 | — | — | CN | claimed |
| CN-110869375-B | 2-oxo-1-imidazolidinylimidazothiadiazole derivatives | UCB生物制药有限责任公司 | 2022-08-30 | — | — | CN | claimed |
| EP-3724198-B1 | 2-OXO-1-PYRROLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB Biopharma SRL (BE) | 2022-02-16 | — | — | EP | claimed |
| US-4362728-A | Haloguanidine compounds, pharmaceutical compositions and methods of use | ICI AMERICAS INC. (US) | 1982-12-07 | — | — | US | claimed |
| EP-0065823-A1 | Heterocyclic guanidines as histamine H-2 antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | claimed |
| EP-0061318-A2 | Guanidinoheterocyclic derivatives as histamine H-2 antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-29 | — | — | EP | claimed |
| EP-0060697-A1 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060730-A2 | Bicyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060696-A1 | Nitrogen heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060094-A2 | Guanidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | claimed |
| EP-0059597-A2 | Guanidino-substituted heterocyclic derivatives having histamine H-2 antagonist activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-08 | — | — | EP | claimed |
| EP-0045155-A1 | Guanidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-03 | — | — | EP | claimed |
| EP-0030092-A1 | Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-06-10 | — | — | EP | claimed |