Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18771492 | 1.00 | DPP4 (0.39) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL18771558 | 1.00 | DPP4 (0.39) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL18771493 | 0.83 | DPP4 (0.36) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL18771529 | 0.83 | DPP4 (0.36) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL20629796 | 0.82 | CHRM2 (0.32) | — | |
| SCHEMBL18771733 | 0.82 | CHRM2 (0.32) | — | |
| SCHEMBL18771738 | 0.82 | CHRM2 (0.32) | — | |
| SCHEMBL18771496 | 0.79 | DPP4 (0.41) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL21086473 | 0.79 | DPP4 (0.41) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL18771237 | 0.79 | DPP4 (0.41) | DPP4DPP8PREPFAPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825312-A1 | INTERMEDIATES FOR PREPARING INHIBITORS OF HEPATITIS C VIRUS | Gilead Pharmasset LLC (US) | 2021-05-26 | — | — | EP | disclosed |
| EP-3492464-A1 | INTERMEDIATES FOR PREPARING INHIBITORS OF HEPATITIS C VIRUS | Gilead Sciences, Inc. (US) | 2019-06-05 | — | — | EP | disclosed |