Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31689407 | 0.74 | HPGD (0.55) | KMT2APKMTSHRSMN1; SMN2HPGD | |
| SCHEMBL31752032 | 0.73 | KMT2A (0.63) | KMT2APKMTSHRSMN1; SMN2HPGD | |
| SCHEMBL6755812 | 0.71 | HPGD (0.50) | ALDH1A1KMT2APKMTSHRSMN1; SMN2 | |
| SCHEMBL7945209 | 0.70 | CASP3 (0.55) | KMT2ATSHRPOLBPABPC1ALOX15 | |
| SCHEMBL12905303 | 0.70 | HDAC1 (0.68) | ALDH1A1KMT2AHPGDPOLBHDAC1 | |
| SCHEMBL17432061 | 0.69 | KMT2A (0.49) | KMT2APKMTSHRSMN1; SMN2HPGD | |
| SCHEMBL540514 | 0.69 | CASP3 (0.62) | ALDH1A1KMT2APKMTSHRSMN1; SMN2 | |
| SCHEMBL29802648 | 0.69 | CASP3 (0.62) | ALDH1A1KMT2APKMTSHRSMN1; SMN2 | |
| SCHEMBL9757668 | 0.69 | KMT2A (0.56) | ALDH1A1KMT2APKMTSHRSMN1; SMN2 | |
| SCHEMBL17866111 | 0.69 | KMT2A (0.56) | ALDH1A1KMT2APKMTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253333-B1 | Contrast Agents for Myocardial Perfusion Imaging | LANTHEUS MEDICAL IMAGING INC (US) | 2019-06-12 | — | — | EP | disclosed |