SCHEMBL2108714

SCHEMBL2108714

COC(OC)C(C)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5698961 1.00
SCHEMBL5699107 1.00
SCHEMBL28070937 0.79 ALDH1A1 (0.31)
SCHEMBL5832236 0.76
SCHEMBL28764918 0.75
SCHEMBL12477466 0.74 TSHR (0.48)
SCHEMBL5889382 0.72 ALDH1A1 (0.39)
SCHEMBL9007374 0.72
SCHEMBL14445167 0.72
SCHEMBL222668 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9616459-B1 Polymeric coatings for fortification of visible, infrared, and laser optical devices LOCKHEED MARTIN CORPORATION (US) 2017-04-11 US claimed
CN-103664614-A Preparation method of ether ester compound CHINA PETROLEUM & CHEMICAL 2014-03-26 CN claimed
EP-2173705-A1 PROCESS FOR THE SYNTHESIS OF CARBAMATES USING CO2 Huntsman International LLC (US) 2010-04-14 EP claimed
WO-2009013062-A1 PROCESS FOR THE SYNTHESIS OF CARBAMATES USING CO2 HUNTSMAN INTERNATIONAL LLC (US) 2009-01-29 WO claimed
WO-1997015683-A9 ENZYMATIC SYNTHESIS OF L-FUCOSE AND L-FUCOSE ANALOGS 1997-10-02 WO claimed
WO-1997015683-A1 ENZYMATIC SYNTHESIS OF L-FUCOSE AND L-FUCOSE ANALOGS THE SCRIPPS RESEARCH INSTITUTE (US) 1997-05-01 WO claimed
EP-0560408-A1 Enantio- and regioselective syntheses of organic compounds using enol esters as irreversible transacylation reagents G.D. SEARLE & CO. (US) 1993-09-15 EP claimed
EP-0357009-A2 Method of resolution of hydroxy-cyclopentenones using a lipase and transacylation agents G.D. Searle & Co. (US) 1990-03-07 EP claimed
US-12552783-B2 Modulators of proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-17 US disclosed
EP-4305038-B1 KRAS G12D INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2025-01-29 EP disclosed
US-20240317769-A1 KRAS G12D INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2024-09-26 US disclosed
CN-118525039-A Olefin metathesis polymerization catalyst system and curable compositions containing the same 特伦尼有限公司 2024-08-20 CN disclosed
EP-4305038-A1 KRAS G12D INHIBITORS Bristol-Myers Squibb Company (US) 2024-01-17 EP disclosed
CN-117242074-A KRAS G12D inhibitors 百时美施贵宝公司 2023-12-15 CN disclosed
US-4925869-A REACTIVATING ENZYME ACETYLCHOLINESTERASE INHIBITED BY LETHAL DOSE OF SOMAN IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-05-15 US disclosed
US-4921979-A THROMBOXANE A2 ANTAGONISTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-05-01 US disclosed
EP-0357009-A2 Method of resolution of hydroxy-cyclopentenones using a lipase and transacylation agents G.D. Searle & Co. (US) 1990-03-07 EP disclosed
US-4775684-A 1,3-dioxane ethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-10-04 US disclosed
EP-0266979-A2 Therapeutic agents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-11 EP disclosed
EP-0201351-A2 1,3-Dioxane ethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-11-12 EP disclosed