Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19369844 | 1.00 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19369591 | 1.00 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19369592 | 1.00 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19369593 | 1.00 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19369759 | 1.00 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19369590 | 1.00 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19369842 | 1.00 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21087033 | 1.00 | TSHR (0.52) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL352570 | 0.96 | — | — | |
| SCHEMBL30480105 | 0.90 | TSHR (0.66) | TSHRSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263948-A | Compounds and conjugates thereof | 免疫医疗有限公司 | 2023-12-22 | — | — | CN | claimed |
| US-20190175744-A1 | INSULIN-INCRETIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2019-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190175744-A1 | INSULIN-INCRETIN CONJUGATES | GIPR, GLP1R, GCGR | TSHR 116/4885SLC1A3 1331/4885SLC1A2 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.