⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19369591 | 0.96 | TSHR (0.52) | — | |
| SCHEMBL19369844 | 0.96 | TSHR (0.52) | — | |
| SCHEMBL19369759 | 0.96 | TSHR (0.52) | — | |
| SCHEMBL19369842 | 0.96 | TSHR (0.52) | — | |
| SCHEMBL19369590 | 0.96 | TSHR (0.52) | — | |
| SCHEMBL19369592 | 0.96 | TSHR (0.52) | — | |
| SCHEMBL19369593 | 0.96 | TSHR (0.52) | — | |
| SCHEMBL21087033 | 0.96 | TSHR (0.52) | — | |
| SCHEMBL21087209 | 0.96 | TSHR (0.52) | — | |
| SCHEMBL20346428 | 0.85 | TSHR (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265429-A1 | SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF | Arrowhead Pharmaceuticals, Inc. | 2023-08-24 | — | — | US | disclosed |
| EP-4149550-A1 | TOLL-LIKE RECEPTOR (TLR) AGONIST NANOPARTICLES AND USES THEREOF | The Board of Trustees of the Leland Stanford Junior University (US) | 2023-03-22 | — | — | EP | disclosed |
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |