Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28018617 | 0.97 | LMNA (0.72) | LMNACYP3A4KDM4EMAPTHTT | |
| Acetic Acid SCHEMBL7902877 | 0.90 | LMNA (0.77) | LMNACYP3A4KDM4EMAPTHTT | |
| Acetic Acid SCHEMBL9177085 | 0.90 | LMNA (0.77) | LMNACYP3A4KDM4EMAPTHTT | |
| Acetic Acid SCHEMBL7908727 | 0.89 | LMNA (0.74) | LMNACYP3A4KDM4EMAPTHTT | |
| Trifluoroacetic Acid SCHEMBL27861726 | 0.87 | LMNA (0.62) | LMNACYP3A4KDM4EMAPTHTT | |
| SCHEMBL28527433 | 0.87 | LMNA (0.89) | LMNACYP3A4KDM4EMAPTHTT | |
| Methyl Alcohol SCHEMBL27642901 | 0.87 | LMNA (0.89) | LMNACYP3A4KDM4EMAPTHTT | |
| Hydrochloric Acid SCHEMBL28463976 | 0.87 | LMNA (0.96) | LMNACYP3A4KDM4EMAPTHTT | |
| Methyl Alcohol SCHEMBL27878296 | 0.85 | LMNA (0.85) | LMNACYP3A4KDM4EMAPTHTT | |
| SCHEMBL28409497 | 0.85 | LMNA (0.68) | LMNACYP3A4KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281382-B1 | OXIDATION CATALYSTS | GEORGIA TECH RESEARCH CORP. | 2001-08-28 | — | — | US | claimed |
| JP-5221908-A | — | — | None | — | — | JP | disclosed |
| US-20220162480-A1 | ADHESIVE COMPOSITION, ADHESIVE TAPE, AND METHOD FOR PROCESSING ELECTRONIC COMPONENT | SEKISUI CHEMICAL CO., LTD. (JP) | 2022-05-26 | — | — | US | disclosed |
| CN-113574083-A | Adhesive composition, adhesive tape, and method for processing electronic component | 积水化学工业株式会社 | 2021-10-29 | — | — | CN | disclosed |
| US-20210301133-A1 | CURABLE POLYIMIDES | DESIGNER MOLECULES INC (US) | 2021-09-30 | — | — | US | disclosed |
| WO-2020189764-A1 | ADHESIVE COMPOSITION, ADHESIVE TAPE, AND METHOD FOR PROCESSING ELECTRONIC COMPONENT | 積水化学工業株式会社 | 2020-09-24 | — | — | WO | disclosed |
| CN-111108144-A | Curable polyimide | 设计分子有限公司 | 2020-05-05 | — | — | CN | disclosed |
| EP-3642262-A1 | CURABLE POLYIMIDES | Designer Molecules, Inc. (US) | 2020-04-29 | — | — | EP | disclosed |
| WO-2018237377-A1 | CURABLE POLYIMIDES | DESIGNER MOLECULES, INC (US) | 2018-12-27 | — | — | WO | disclosed |
| US-8158748-B2 | Hetero-functional compounds and methods for use thereof | DESIGNER MOLECULES, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| WO-1998014997-A1 | METHOD AND APPARATUS USEFUL FOR THE PREPARATION OF LEAD-ON-CHIP ASSEMBLIES | QUANTUM MATERIALS, INC. (US) | 1998-04-09 | — | — | WO | disclosed |
| EP-0522069-B1 | METHOD TO IMPART COFFEE STAIN RESISTANCE TO POLYAMIDE TEXTILE SUBSTRATES | ALLIED SIGNAL INC (US) | 1995-05-24 | — | — | EP | disclosed |
| US-5364541-A | Method to impart coffee stain resistance to polyamide textile substrates | ALLIEDSIGNAL INC. | 1994-11-15 | — | — | US | disclosed |
| US-5359010-A | Phenoxy- or naphthyloxy-acrylic acid ester-maleic acid copolymers as antisoilants for nylon carpets or upholstery | ALLIEDSIGNAL INC. (US) | 1994-10-25 | — | — | US | disclosed |
| JP-H05221908-A | PREPARATION OF MONOVINYL ETHER | BASF AG | 1993-08-31 | — | — | JP | disclosed |
| EP-0522069-A1 | METHOD TO IMPART COFFEE STAIN RESISTANCE TO POLYAMIDE TEXTILE SUBSTRATES. | ALLIED SIGNAL INC (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5135774-A | Using polymer protective coatings | ALLIED-SIGNAL INC. (US) | 1992-08-04 | — | — | US | disclosed |
| US-5118551-A | Method to impart stain resistance to polyamide textile substrates | ALLIED-SIGNAL INC. (US) | 1992-06-02 | — | — | US | disclosed |
| WO-1992005135-A1 | PREPARATION OF PERFLUOROALKYL-ALKYLENE VINYL ETHERS | ALLIED-SIGNAL INC. (US) | 1992-04-02 | — | — | WO | disclosed |
| WO-1991014818-A1 | METHOD TO IMPART COFFEE STAIN RESISTANCE TO POLYAMIDE TEXTILE SUBSTRATES | ALLIED-SIGNAL INC. (US) | 1991-10-03 | — | — | WO | disclosed |