Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22591956 | 0.77 | TDP1 (0.62) | HTR2BHTR2AHTR2CLMNAMAPT | |
| SCHEMBL14785507 | 0.76 | MAPT (0.65) | PTGDR2HTR2BHTR2AHTR2CLMNA | |
| SCHEMBL19498479 | 0.75 | PTGDR2 (0.51) | PTGDR2HTR2BHTR2AHTR2CLMNA | |
| SCHEMBL10093048 | 0.75 | AGPAT2 (0.57) | LMNAKDM4EKMT2AAGPAT2MEN1 | |
| SCHEMBL220452 | 0.75 | NPC1 (0.59) | PTGDR2HTR2BHTR2AHTR2CMAPT | |
| SCHEMBL19282854 | 0.74 | PTGDR2 (0.52) | PTGDR2HTR2BHTR2AHTR2CMAPT | |
| SCHEMBL28542896 | 0.74 | HTR2B (0.51) | PTGDR2HTR2BHTR2AHTR2CMAPT | |
| SCHEMBL1006487 | 0.74 | NPC1 (0.52) | HTR2BHTR2AHTR2CLMNAMAPT | |
| SCHEMBL30451996 | 0.74 | NPC1 (0.52) | HTR2BHTR2AHTR2CLMNAMAPT | |
| SCHEMBL4232630 | 0.74 | HTR2B (0.51) | PTGDR2HTR2BHTR2AHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191445-B1 | CYCLOBUTANE CONTAINING CARBOXYLIC ACID GPR120 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2019-06-12 | — | — | EP | disclosed |