Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006487 | 1.00 | NPC1 (0.52) | NPC1ALDH1A1LMNARAB9AMAPT | |
| SCHEMBL22591956 | 0.83 | TDP1 (0.62) | ALDH1A1LMNAMAPTHTR2BHTR2A | |
| SCHEMBL5752867 | 0.81 | SMN1; SMN2 (0.54) | NPC1ALDH1A1LMNARAB9AMAPT | |
| SCHEMBL14785169 | 0.81 | HTR2B (0.52) | ALDH1A1MAPTHTR2BHTR2AHTR2C | |
| SCHEMBL28542896 | 0.80 | HTR2B (0.51) | ALDH1A1MAPTHTR2BHTR2AHTR2C | |
| SCHEMBL4232630 | 0.80 | HTR2B (0.51) | NPC1ALDH1A1RAB9AHTR2BHTR2A | |
| SCHEMBL16005094 | 0.80 | PKM (0.64) | NPC1ALDH1A1LMNARAB9AMAPT | |
| SCHEMBL14785507 | 0.79 | MAPT (0.65) | NPC1ALDH1A1LMNAMAPTHTR2B | |
| SCHEMBL19498479 | 0.78 | PTGDR2 (0.51) | NPC1LMNAMAPTHTR2BHTR2A | |
| SCHEMBL1369311 | 0.78 | TDP1 (0.70) | NPC1ALDH1A1LMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |