Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25739576 | 0.86 | — | — | |
| SCHEMBL24754156 | 0.73 | ESR2 (0.32) | — | |
| SCHEMBL1703765 | 0.66 | PLG (0.55) | NCF1PLGPLATLMNA | |
| SCHEMBL432248 | 0.66 | PLG (0.55) | NCF1PLGPLATLMNA | |
| SCHEMBL6802 | 0.66 | — | — | |
| SCHEMBL48375 | 0.66 | PLG (0.55) | NCF1PLGPLATLMNA | |
| SCHEMBL1956833 | 0.65 | PLG (0.39) | NCF1PLGPLATLMNA | |
| SCHEMBL1700941 | 0.65 | PLG (0.39) | NCF1PLGPLATLMNA | |
| SCHEMBL13950191 | 0.65 | PLG (0.39) | NCF1PLGPLATLMNA | |
| SCHEMBL1159829 | 0.65 | PLG (0.39) | NCF1PLGPLATLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558446-B1 | NOVEL COMPOUNDS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID OR AMYLOID-LIKE PROTEINS | AC IMMUNE SA (CH) | 2019-06-12 | — | — | EP | disclosed |