Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25893655 | 0.88 | — | — | |
| SCHEMBL18637323 | 0.82 | — | — | |
| SCHEMBL25596510 | 0.75 | — | — | |
| SCHEMBL25739575 | 0.74 | — | — | |
| SCHEMBL21088255 | 0.73 | NCF1 (0.34) | — | |
| SCHEMBL240852 | 0.69 | ESR2 (0.50) | ESR2 | |
| SCHEMBL5733 | 0.69 | — | — | |
| SCHEMBL24197652 | 0.69 | ESR2 (0.50) | ESR2 | |
| SCHEMBL18637326 | 0.69 | — | — | |
| SCHEMBL11704042 | 0.68 | ESR2 (0.38) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023049808-A2 | SMALL MOLECULE INHIBITORS OF TEAD-YAP | THE GENERAL HOSPITAL CORPORATION (US) | 2023-03-30 | — | — | WO | disclosed |
| WO-2022261250-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |