Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18182909 | 1.00 | KDM1A (0.50) | KDM1ACTSKSLC9A1MAPTLMNA | |
| SCHEMBL21088849 | 0.82 | KDM1A (0.49) | KDM1ACTSKMAPTLMNASMN1; SMN2 | |
| SCHEMBL21088859 | 0.80 | KDM1A (0.58) | KDM1ACTSKMAPTLMNASMN1; SMN2 | |
| SCHEMBL21088669 | 0.80 | KDM1A (0.58) | KDM1ACTSKMAPTLMNASMN1; SMN2 | |
| SCHEMBL18172735 | 0.79 | KDM1A (0.56) | KDM1ACTSKMAPTLMNASMN1; SMN2 | |
| SCHEMBL18173266 | 0.79 | KDM1A (0.56) | KDM1ACTSKMAPTLMNASMN1; SMN2 | |
| SCHEMBL18172738 | 0.79 | KDM1A (0.56) | KDM1ACTSKMAPTLMNASMN1; SMN2 | |
| SCHEMBL18173141 | 0.78 | KDM1A (0.45) | KDM1ACTSKMAPTLMNASMN1; SMN2 | |
| SCHEMBL18173167 | 0.78 | KDM1A (0.45) | KDM1ACTSKMAPTLMNASMN1; SMN2 | |
| SCHEMBL18173146 | 0.78 | KDM1A (0.45) | KDM1ACTSKMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |