Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.77 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA9 | Q16790 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229994 | 0.90 | RECQL (0.88) | RECQLCA12CA9POLBPLCG1 | |
| SCHEMBL10453957 | 0.86 | RECQL (0.59) | RECQLCA12CA9POLBCA1 | |
| SCHEMBL4529161 | 0.85 | RECQL (0.66) | RECQLCA12CA9POLBPLCG1 | |
| SCHEMBL766259 | 0.82 | RECQL (0.62) | RECQLPOLBPLCG1CA1CA2 | |
| SCHEMBL15916047 | 0.82 | RECQL (0.62) | RECQLCA12CA9POLBPLCG1 | |
| SCHEMBL634315 | 0.80 | CA12 (0.61) | RECQLCA12CA9POLBCA1 | |
| SCHEMBL32664495 | 0.80 | CA12 (0.61) | RECQLCA12CA9POLBCA1 | |
| SCHEMBL15915838 | 0.79 | RECQL (0.68) | RECQLCA12CA9POLBPLCG1 | |
| SCHEMBL15915771 | 0.79 | RECQL (0.59) | RECQLL3MBTL1 | |
| SCHEMBL15916204 | 0.79 | RECQL (0.58) | RECQLCA12CA9POLBPLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495359-A1 | FLAP MODULATORS | Janssen Pharmaceutica NV (BE) | 2019-06-12 | — | — | EP | disclosed |