Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1459251 | 0.98 | EPHX1 (0.44) | EPHX1GAABTKEPHX2HDAC4 | |
| SCHEMBL3666819 | 0.84 | EPHX2 (0.41) | EPHX1GAAEPHX2NPSR1KDM4E | |
| Hydrochloric Acid SCHEMBL1458776 | 0.83 | EPHX2 (0.40) | EPHX1EPHX2NPSR1KDM4EPOLB | |
| SCHEMBL3988453 | 0.82 | POLB (0.48) | EPHX1GAAEPHX2NPSR1KDM4E | |
| SCHEMBL1203989 | 0.80 | POLB (0.46) | GAAEPHX2KDM4EPOLBL3MBTL1 | |
| SCHEMBL21088943 | 0.79 | EPHX1 (0.41) | EPHX1EPHX2NPSR1KDM4EPOLB | |
| SCHEMBL13846152 | 0.77 | SMN1; SMN2 (0.40) | EPHX1EPHX2KDM4EPOLBPDK1 | |
| SCHEMBL11373425 | 0.76 | EPHX1 (0.49) | EPHX1GAABTKEPHX2HDAC4 | |
| SCHEMBL2547400 | 0.76 | EPHX1 (0.49) | EPHX1GAABTKEPHX2HDAC4 | |
| Hydrochloric Acid SCHEMBL630248 | 0.75 | EPHX1 (0.48) | EPHX1GAABTKEPHX2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |