Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644041 | 0.79 | MEN1 (0.46) | MEN1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL17501350 | 0.76 | MALT1 (0.39) | MEN1RAB9AKMT2AKDM1AMAOA | |
| SCHEMBL3217424 | 0.72 | KDM1A (0.57) | MEN1RAB9AKMT2AKDM1AMAOA | |
| SCHEMBL26944359 | 0.72 | KDM4E (0.49) | MEN1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL31172011 | 0.72 | KDM1A (0.57) | MEN1RAB9AKMT2AKDM1AMAOA | |
| SCHEMBL11936117 | 0.71 | MEN1 (0.58) | MEN1RAB9AKMT2AHRH3GRIN2B | |
| SCHEMBL10073807 | 0.71 | MEN1 (0.69) | MEN1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL12953631 | 0.70 | POLB (0.37) | KDM1AMAOAMAOBPOLBLMNA | |
| SCHEMBL13305056 | 0.70 | KDM4E (0.39) | KDM4EPOLBLMNA | |
| SCHEMBL2644039 | 0.70 | VNN1 (0.53) | MEN1RAB9AKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |