Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23494611 | 1.00 | OPRK1 (0.79) | OPRK1OPRM1 | |
| SCHEMBL21090020 | 1.00 | OPRK1 (0.79) | OPRK1OPRM1 | |
| SCHEMBL21090032 | 1.00 | OPRK1 (0.79) | OPRK1OPRM1 | |
| SCHEMBL23515446 | 1.00 | OPRK1 (0.79) | OPRK1OPRM1 | |
| SCHEMBL21090036 | 1.00 | OPRK1 (0.79) | OPRK1OPRM1 | |
| SCHEMBL3765258 | 0.89 | OPRK1 (1.00) | OPRK1OPRM1 | |
| SCHEMBL23515478 | 0.88 | OPRK1 (0.81) | OPRK1OPRM1 | |
| SCHEMBL23515477 | 0.88 | OPRK1 (0.81) | OPRK1OPRM1 | |
| SCHEMBL21090624 | 0.88 | OPRK1 (0.81) | OPRK1OPRM1 | |
| SCHEMBL21090136 | 0.88 | OPRK1 (0.81) | OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113419-A1 | PYRANO[3,4-B]PYRAZINE KAPPA OPIOID RECEPTOR LIGANDS FOR TREATING ADDICTION, PRURITUS, PAIN, AND INFLAMMATION | THE ROCKEFELLER UNIVERSITY (US) | 2019-06-13 | — | — | WO | disclosed |