Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.68 |
| ▸ | DRD2 | P14416 | 4/20 | 0.68 |
| ▸ | HRH1 | P35367 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.66 |
| ▸ | DRD1 | P21728 | 4/20 | 0.66 |
| ▸ | HTR2A | P28223 | 4/20 | 0.66 |
| ▸ | HTR2C | P28335 | 4/20 | 0.66 |
| ▸ | HTR3A | P46098 | 3/20 | 0.66 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.66 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.66 |
| ▸ | HTR6 | P50406 | 3/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etolotifen SCHEMBL10851254 | 0.99 | DRD3 (0.67) | DRD3DRD2HRH1LMNACHRM2 | |
| SCHEMBL10848583 | 0.87 | DRD3 (0.52) | DRD3DRD2HRH1LMNACHRM2 | |
| SCHEMBL10848598 | 0.87 | DRD3 (0.52) | DRD3DRD2HRH1LMNACHRM2 | |
| SCHEMBL9844348 | 0.83 | DRD3 (0.75) | DRD3DRD2HRH1LMNACHRM2 | |
| SCHEMBL9844340 | 0.83 | DRD3 (0.72) | DRD3DRD2HRH1LMNACHRM2 | |
| Hydroxyzine SCHEMBL138224 | 0.83 | DRD3 (0.57) | DRD3DRD2HRH1LMNACHRM2 | |
| SCHEMBL9844341 | 0.82 | DRD3 (0.77) | DRD3DRD2HRH1LMNACHRM2 | |
| Hydrochloric Acid SCHEMBL9844418 | 0.82 | DRD3 (0.74) | DRD3DRD2HRH1LMNACHRM2 | |
| Hydrochloric Acid SCHEMBL9844514 | 0.82 | DRD3 (0.71) | DRD3DRD2HRH1LMNACHRM2 | |
| Hydrochloric Acid SCHEMBL9844566 | 0.82 | DRD3 (0.75) | DRD3DRD2HRH1LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| US-4609664-A | ANTIALLERGIC | SANDOZ LTD. (CH) | 1986-09-02 | — | — | US | claimed |
| EP-0047226-B1 | PIPERIDYLIDENE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANDOZ AG (CH) | 1985-05-15 | — | — | EP | claimed |
| EP-0047226-A2 | Piperidylidene derivatives, their production and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1982-03-10 | — | — | EP | claimed |
| US-11598774-B2 | Methods of diagnosis and treatment of Alzheimer's Disease | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-07 | — | — | US | disclosed |
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| US-11191719-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200088724-A1 | METHODS OF DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-03-19 | — | — | US | disclosed |
| US-10577406-B2 | FKBP-L polypeptides and uses in angiogenesis-mediated disorders | ALMAC DISCOVERY LIMITED (GB) | 2020-03-03 | — | — | US | disclosed |
| EP-0345931-A1 | Certain PAF antagonist/antihistamine combinations and methods | SCHERING CORPORATION (US) | 1989-12-13 | — | — | EP | disclosed |
| WO-1989010143-A1 | CERTAIN PAF ANTAGONIST ANTIHISTAMINE COMBINATIONS AND METHODS | SCHERING CORPORATION (US) | 1989-11-02 | — | — | WO | disclosed |
| US-4609664-A | ANTIALLERGIC | SANDOZ LTD. (CH) | 1986-09-02 | — | — | US | disclosed |
| EP-0047226-B1 | PIPERIDYLIDENE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANDOZ AG (CH) | 1985-05-15 | — | — | EP | disclosed |
| EP-0047226-A2 | Piperidylidene derivatives, their production and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1982-03-10 | — | — | EP | disclosed |