Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17168810 | 0.83 | RORC (0.60) | RORC | |
| SCHEMBL17168858 | 0.83 | RORC (0.59) | RORC | |
| SCHEMBL17171550 | 0.82 | RORC (0.60) | RORC | |
| SCHEMBL17168862 | 0.82 | RORC (0.60) | RORC | |
| SCHEMBL17168829 | 0.79 | RORC (0.61) | RORC | |
| SCHEMBL21090727 | 0.79 | RORC (0.44) | RORC | |
| SCHEMBL17171402 | 0.79 | RORC (0.65) | RORC | |
| SCHEMBL25812631 | 0.77 | RORC (0.57) | RORC | |
| SCHEMBL21090254 | 0.76 | RORC (0.51) | RORC | |
| SCHEMBL17168765 | 0.75 | RORC (0.67) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131902-B1 | COMPOUNDS AS MODULATORS OF ROR GAMMA | BOEHRINGER INGELHEIM INT (DE) | 2019-06-12 | — | — | EP | disclosed |