Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21089764 | 0.88 | PTK2 (0.33) | CA2CA1PTK2HRH4PDGFRA | |
| SCHEMBL21054186 | 0.70 | CA2 (0.31) | CA2CA9 | |
| SCHEMBL17097221 | 0.67 | CA9 (0.58) | CA2CA1CA9CA12CA4 | |
| SCHEMBL16278118 | 0.65 | CA2 (0.53) | CA2CA1CA9CA12CA4 | |
| SCHEMBL16277462 | 0.65 | TP53 (0.38) | CA2CA1PTK2CA9CA12 | |
| SCHEMBL16283536 | 0.64 | PTK2 (0.34) | CA2CA1PTK2CA9CA12 | |
| SCHEMBL22226932 | 0.64 | CA9 (0.58) | CA2CA9CA12 | |
| SCHEMBL11693134 | 0.63 | HTT (0.39) | CA2CA1HRH4CA9CA12 | |
| SCHEMBL11693059 | 0.61 | CA2 (0.45) | CA2CA1PTK2CDK5TYRO3 | |
| SCHEMBL18659731 | 0.61 | NR1I2 (0.39) | CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112719-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | ANGEX PHARMACEUTICAL, INC. (US) | 2019-06-13 | — | — | WO | disclosed |